Socio-Demographic and Clinical Characteristics and Outcomes of COVID-19 Patients in Kaduna State
DOI:
https://doi.org/10.54987/jobimb.v11i1.798Keywords:
Socio-Demographic, Clinical characteristics, Covid-19, Kaduna, NigeriaAbstract
Advancing age and male sex were found to contribute to the fatal presentation and outcome of COVID-19 infection. Identifying factors associated with severity of presentation and mortality could improve management of COVID-19. A descriptive study to describe sociodemographic and clinical characteristics/profile and outcome of COVID-19 patients in Kaduna state with highest cases in Northern Nigeria was conducted to explore determinants of severity and overall mortality. A retrospective cross-sectional review of clinical records of 902 COVID-19 patients from 27th March, 2020 to 31st December, 2021 in the 4 isolation centers in the state was conducted. Data was analyzed using SPSS 26 and STATA SE 12 at P ≤ 0.05.Out of the nine-hundred and two (902) that satisfied the inclusion criteria, the majority were 40 years and below 496 (55%), mean age ± S.D was 40.1 ± 16.0. Majority were Males 524 (58.1%), Christians 494 (54.8%), and Non-southern Kaduna tribes 593 (65.7%). The duration of illness was found to be prolonged among the elderly males (9.36 ± 3.79) compared to females (8.5 ± 3.20days). Bivariate analysis revealed that age (X2 = 51.20 P=0.0001), Religion (X2 = 6.51 P=0.011), Marital status (X2 = 7.89 P=0.005), occupation (X2 = 7.80 P=0.005) and presence of comorbidities significantly affected the severity of clinical presentation and overall mortality among COVID-19 patients. Sex was only found to have an effect on severity of clinical symptoms (X2 = 9.90 P=0.002), but not overall mortality (X2 = 2.24 P=0.13). Age, religion, marital status, occupation and presence of comorbidity were predictors of worst clinical characteristics and mortality of COVID-19 in Kaduna State.
References
Vargas JRN. The COVID-19 pandemic. Rev Facul Med. 2020:68;7-8.
Almalki ZS, Khan MF, Almazrou S, Alanazi AS, Iqbal MS, Alqahtani A, et al. Clinical characteristics and outcomes among COVID-19 hospitalized patients with chronic conditions: A retrospective single-center study. J Multidiscip Healthc. 2020;13:1089-97.
Klein SL, Morgan R. The impact of sex and gender on immunotherapy outcomes. Biol Sex Differ. 2020;11(1):1-13.
Ortolan A, Lorenzin M, Felicetti M, Doria A, Ramonda R. Does gender influence clinical expression and disease outcomes in COVID-19? A systematic review and meta-analysis. Int J Infect Dis. 2020;99:496-504.
Alizadehsani R, Alizadeh Sani Z, Behjati M, Roshanzamir Z, Hussain S, Abedini N, et al. Risk factors prediction, clinical outcomes, and mortality in COVID-19 patients. J Med Virol. 2021;93(4):2307-2320.
Jamil M, Bhattacharya P, Barman B, Topno N, Barman H, Nongpiur VN, War G, Hynniewta Y, Saikia B, Naku N, Bhattacharya PK. Clinical and demographic profile of COVID-19 patients: a tertiary level hospital-based study from Northeast India. Cureus J Med Sci. 2021;13(10).
El Aidaoui K, Haoudar A, Khalis M, Kantri A, Ziati J, El Ghanmi A, Bennis G, El Yamani K, Dini N, El Kettani C. Predictors of severity in Covid-19 patients in Casablanca, Morocco. Cureus. 2020;12(9).
Whisenant J, Wong S, Torri V, Revuelta J, Halmos B, Ceresoli G, et al. P09.18 COVID-19 Outcomes in Patients with Thoracic Malignancies According to Gender and Ethnicity (TERAVOLT). J Thorac Oncol. 2021;16(3): S297.
Su YJ, Kuo KC, Wang TW, Chang CW. Gender-based differences in COVID-19. New Microbes New Infect. 2021; 42:1-6.
Richardson S, Hirsch JS, Narasimhan M, Crawford JM, McGinn T, Davidson KW, et al. Presenting Characteristics, Comorbidities, and Outcomes among 5700 Patients Hospitalized with COVID-19 in the New York City Area. JAMA - J Am Med Assoc. 2020;323(20).
Ramatillah DL, Isnaini S. Treatment profiles and clinical outcomes of COVID-19 patients at private hospital in Jakarta. PLoS One. 2021;16(4):e0250147.
Idris U, Oyefabi AM, Dalhat MM, Umar IM, Abdulmajid M, Gwamna J, et al. Treatment Outcomes in COVID-19 patients with comorbidities in Kaduna state, Northwestern Nigeria. Niger Health J. 2023;23(1):517-23.
Osibogun A, Balogun M, Abayomi A, Idris J, Kuyinu Y, Odukoya O, et al. Outcomes of COVID-19 patients with comorbidities in southwest Nigeria. PLoS One. 2021;16(3):p.e0248281.
Albadawy RM, Jadoon BA, Mogahed MM, Ibrahim ME, Essawy TS, Amin AMA, et al. The Impact of Comorbidities on the Outcomes of Egyptian COVID-19 Patients: A Follow-Up Study. J Environ Public Health. 2021;2021.
Oyefabi A, Musa S, Kambai H, Usman I, Gwamna J, Sheyin J, et al. Comparison of the Ivermectin and Lopinavir/Ritonavir Treatment Outcomes among COVID-19 Mild to Moderate Cases in Kaduna State. West Afr J Med. 2022;39(2).
Alkundi A, Mahmoud I, Musa A, Naveed S, Alshawwaf M. Clinical characteristics and outcomes of COVID-19 hospitalized patients with diabetes in the United Kingdom: A retrospective single centre study. Diabetes Res Clin Pract. 2020;165.
Mohan A, Tiwari P, Bhatnagar S, Patel A, Maurya A, Dar L, et al. Clinico-demographic profile & hospital outcomes of COVID-19 patients admitted at a tertiary care centre in north India. Indian J Med Res. 2020;152(1):61.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Journal of Biochemistry, Microbiology and Biotechnology

This work is licensed under a Creative Commons Attribution 4.0 International License.
Authors who publish with this journal agree to the following terms:
- Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0) that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.
- Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
- Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access).