Determination of MIC and NIC values of Allivum sativum methanolic extract against Aeromonas hydrophila

Authors

  • Ahmad Syazwan Ismail Biotechnology and Nanotechnology Research Centre, Malaysian Agricultural Research and Development Institute (MARDI), Persiaran MARDI-UPM, 43400 Serdang, Selangor, Malaysia.
  • Mohd Yunus Shukor Department of Biochemistry, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, D.E, Malaysia.
  • Noor Azlina Masdor Biotechnology and Nanotechnology Research Centre, Malaysian Agricultural Research and Development Institute (MARDI), Persiaran MARDI-UPM, 43400 Serdang, Selangor, Malaysia.

DOI:

https://doi.org/10.54987/bessm.v6i1.706

Keywords:

Aeromonas hydrophila, Allium sativum, MIC, NIC, Lambert-Pearson model

Abstract

Plant extracts have been studied extensively for their ability to suppress the growth of bacteria. Because these findings were not reported on in the benchmark values, it was not possible to compare the results of this study to other investigations. Nonlinear regression analysis of the data is one of the most accurate methods of determining this value. The minimum inhibitory concentration (MIC) and non-inhibitory concentration (NIC) values of the methanolic extract of Allium sativum against the pathogen Aeromonas hydrophila were successfully determined using Lambert and Pearson's modified Gompertz model. As shown by the model's high correlation coefficient (0.995), garlic's MIC and NIC values of 28.02 mg/mL (95% Confidence Interval from 26.42 to 29.71) and 12.60 mg/mL (95% C.I., 11.88 to 13.37) suggest that it could be used as an inhibitory agent against this essential fish pathogen.

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Published

2022-07-31

How to Cite

Ismail, A. S. ., Shukor, M. Y., & Masdor, N. A. (2022). Determination of MIC and NIC values of Allivum sativum methanolic extract against Aeromonas hydrophila. Bulletin of Environmental Science and Sustainable Management (e-ISSN 2716-5353), 6(1), 25–27. https://doi.org/10.54987/bessm.v6i1.706

Issue

Vol. 6 No. 1 (2022)

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Articles

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